季加孚主任醫(yī)師
北京大學(xué)腫瘤醫(yī)院胃腸腫瘤外科
季加孚：教授、主任醫(yī)師、博士生導(dǎo)師。 現(xiàn)任北京大學(xué)腫瘤醫(yī)院院長(zhǎng)，北京腫瘤醫(yī)院院長(zhǎng)，北京大學(xué)臨床腫瘤學(xué)院院長(zhǎng)，北京市腫瘤防治研究所所長(zhǎng)，教育部惡性腫瘤發(fā)病機(jī)制及轉(zhuǎn)化重點(diǎn)實(shí)驗(yàn)室胃癌研究室主任，北京腫瘤醫(yī)院大外科主任、國(guó)家藥物臨床試驗(yàn)機(jī)構(gòu)主任、生物樣本庫(kù)主任、胃腸腫瘤轉(zhuǎn)化研究實(shí)驗(yàn)室主任、胃癌診療協(xié)作組首席專家、北京市腫瘤防治研究辦公室主任。中國(guó)抗癌協(xié)會(huì)胃癌專業(yè)委員會(huì)主任委員，中華醫(yī)學(xué)會(huì)外科學(xué)分會(huì)全國(guó)委員、國(guó)際合作部主任、胃腸專業(yè)委員會(huì)副主任委員，中國(guó)臨床腫瘤學(xué)會(huì)(CSCO)執(zhí)委會(huì)委員，CSCO腫瘤營(yíng)養(yǎng)治療專家委員會(huì)副主任委員，中國(guó)醫(yī)藥生物技術(shù)協(xié)會(huì)組織生物樣本庫(kù)分會(huì)委員，衛(wèi)生部海峽兩岸醫(yī)藥交流協(xié)會(huì)腫瘤體檢專家委員會(huì)主任委員，老年學(xué)學(xué)會(huì)老年腫瘤專業(yè)委員會(huì)執(zhí)行委員會(huì)常務(wù)委員，中國(guó)醫(yī)師協(xié)會(huì)外科醫(yī)師分會(huì)委員。NCCN胃癌臨床實(shí)踐指南(中國(guó)版) 執(zhí)筆人，衛(wèi)生部胃癌診療規(guī)范執(zhí)筆專家，衛(wèi)生部二級(jí)醫(yī)院胃癌診療規(guī)范執(zhí)筆專家。美國(guó)外科學(xué)院(ACS)會(huì)員，亞洲外科學(xué)會(huì) (ASA)常委，國(guó)際外科醫(yī)師暨胃腸道醫(yī)師協(xié)會(huì)(IASGO)學(xué)術(shù)委員會(huì)委員，國(guó)際胃癌協(xié)會(huì)(IGCA)會(huì)員，歐洲臨床營(yíng)養(yǎng)與代謝學(xué)會(huì)(ESPEN)會(huì)員，歐洲IASGO學(xué)院外科學(xué)客座教授。擔(dān)任《Digestive Surgery》、《Annals of Surgery》(中文)、《中華醫(yī)學(xué)雜志》、《中華胃腸外科雜志》、《中國(guó)實(shí)用外科雜志》等多種國(guó)內(nèi)外期刊的編委。 季加孚教授是國(guó)內(nèi)著名的腫瘤外科學(xué)專家，臨床方面主要從事消化道腫瘤外科工作，積極推廣規(guī)范化手術(shù)、開拓國(guó)內(nèi)胃癌新輔助化療領(lǐng)域。研究方向主要以胃癌的臨床綜合治療和分子機(jī)理為重點(diǎn)，牽頭國(guó)內(nèi)外相關(guān)臨床試驗(yàn)(國(guó)際胃癌CLASSIC研究、結(jié)腸癌MASCOT、ACCElox研究等)，作為項(xiàng)目負(fù)責(zé)人主持和參與消化道腫瘤臨床及基礎(chǔ)科研項(xiàng)目26項(xiàng)，其中國(guó)際合作項(xiàng)目3項(xiàng)、國(guó)家級(jí)9項(xiàng)、省部級(jí)4項(xiàng)。先后承擔(dān)了國(guó)家“十一五”、“十二五”支撐計(jì)劃、國(guó)家“863”項(xiàng)目、國(guó)家自然科學(xué)基金項(xiàng)目、北京市科委重大項(xiàng)目、北京大學(xué)人類疾病基因研究中心項(xiàng)目等多項(xiàng)重大課題的研究。與美國(guó)斯坦福大學(xué)合作研究胃癌特異基因表述譜，同期建立并完善了規(guī)范化標(biāo)本采集及管理的腫瘤組織標(biāo)本庫(kù)。 季加孚教授先后于國(guó)內(nèi)外學(xué)術(shù)期刊發(fā)表論文100余篇，總影響因子達(dá)130.7，編寫和編譯學(xué)術(shù)著作8部。培養(yǎng)碩士、博士研究生，博士后40余人。曾獲北京市科學(xué)技術(shù)進(jìn)步三等獎(jiǎng)、科技部?jī)?yōu)秀論文獎(jiǎng)等獎(jiǎng)勵(lì)，以及北京市總工會(huì)經(jīng)濟(jì)技術(shù)創(chuàng)新標(biāo)兵、中國(guó)抗癌協(xié)會(huì)先進(jìn)工作者等榮譽(yù)稱號(hào)。 代表性論文： 1.Xiao-Hong Wang, Lian-Hai Zhang, Xi-Yao Zhong, Xiao-Fang Xing, Yi-Qiang Liu, Zhao-Jian Niu, Yong Peng, Hong Du, Gui-Guo Zhang, Ying Hu, Ni Liu, Yu-Bing Zhu, Shao-Hua Ge, Wei Zhao, Ai-Ping Lu, Ji-You Li, Jia-Fu Ji. S100A6 overexpression associates with poor prognosis and is epigenetically up-regulated in gastric cancer. American Journal of Pathology. 2010 (Accepted) 2.Ni Liu, Lian-hai Zhang, Hong Du, Ying Hu, Gui-guo Zhang, Xiao-hong Wang, Ji-you Li, and Jia-fu Ji. Overexpression of Endothelial Cell Specific Molecule-1 (ESM-1) in Gastric Cancer. Annals of Surgical Oncology. 2010 (Accepted) 3.Li ZY, Tang L, Zhang LH, Bu ZD, Wu AW, Wu XJ, Zong XL, Wu Q, Shan F, Li SX, Ren H, Zhang XP, Ji JF. Weekly docetaxel and cisplatin plus fluorouracil as a preoperative treatment for gastric cancer patients with synchronous multiple hepatic metastases: a pilot study. Med Oncol. 2009 Dec 5. [Epub ahead of print] 4.Jia SQ, Niu ZJ, Zhang LH, Zhong XY, Shi T, Du H, Zhang GG, Hu Y, Su XL, Ji JF. Identification of prognosis-related proteins in advanced gastric cancer by mass spectrometry-based comparative proteomics. J Cancer Res Clin Oncol. 2009; 135(3):403-411 5.Wu A, Ji J. Adjuvant chemotherapy for gastric cancer or not: a dilemma? J Natl Cancer Inst. 2008;100(6):376-377. 6.Zhong XY, Zhang LH, Jia SQ, Shi T, Niu ZJ, Du H, Zhang GG, Hu Y, Lu AP, Li JY, Ji JF. Positive association of up-regulated Cripto-1 and down-regulated E-cadherin with tumour progression and poor prognosis in gastric cancer. Histopathology. 2008;52(5):560-568. 7.Meng H, Tanigawa N, Hao CY, Dai DJ, Lu CD, Ji JF. Chemoresponse to docetaxel correlates with expression of the survivin splicing variants in patients with gastric cancer. Hepatogastroenterology. 2007;54(79):1934-1940. 8.Hao CY, Ji JF. Surgical treatment of liver metastases of colorectal cancer: Strategies and controversies in 2006. Eur J Surg Oncol. 2006;32(5):473-483. 9.Hao CY, Lu AP, Xing BC, Huang XF, Gao F, Ji JF. Solid pseudopapillary tumor of the pancreas: report of 8 cases in a single institution and review of the Chinese literature. Pancreatology. 2006;6(4):291-296 10.Zhang LH, Tian B, Diao LR, Xiong YY, Tian SF, Zhang BH, Li WM, Ren H, Li Y, Ji JF. Dominant expression of 85-kDa form of cortactin in colorectal cancer. J Cancer Res Clin Oncol. 2006;132(2):113-120. 11.Guo DL, Zhang J, Yuen ST, Tsui WY, Chan AS, Ho C, Ji J, Leung SY, Chen X. Reduced expression of EphB2 that parallels invasion and metastasis in colorectal tumours. Carcinogenesis. 2006;27(3):454-464 12.Zhang LH, Ji JF. Molecular profiling of hepatocellular carcinomas by cDNA microarray. World J Gastroenterol. 2005;11(4):463-468. 13.Zhang J, Su XQ, Wu XJ, Liu YH, Wang H, Zong XN, Wang Y, Ji JF. Effect of body mass index on adenocarcinoma of gastric cardia. World J Gastroenterol. 2003;9(12):2658-2661. 14.Chen X, Leung SY, Yuen ST, Chu KM, Ji JF, Li R, Chan AS, Law S, Troyanskaya OG, Wong J, So S, Botstein D, Brown PO. Variation in gene expression patterns in human gastric cancers. Mol Biol Cell. 2003;14(8):3208-3215. 15.Leung SY, Chen X, Chu KM, Yuen ST, Mathy J, Ji JF, Chan AS, Li R, Law S, Troyanskaya OG, Tu IP, Wong J, So S, Botstein D, Brown PO. Phospholipase A2 group IIA expression in gastric adenocarcinoma is associated with prolonged survival and less frequent metastasis. Proc Natl Acad Sci U S A. 2002;99(25):16203-16208. 16.Ji JF, Chen X, Leung SY, Chi JT, Chu KM, Yuen ST, Li R, Chan AS, Li J, Dunphy N, So S. Comprehensive analysis of the gene expression profiles in human gastric cancer cell lines. Oncogene. 2002;21(42):6549-6556. 17.Chen X, Cheung ST, So S, Fan ST, Barry C, Higgins J, Lai KM, Ji JF, Dudoit S, Ng IO, Van De Rijn M, Botstein D, Brown PO. Gene expression patterns in human liver cancers. Mol Biol Cell. 2002;13(6):1929-1939. 會(huì)議摘要： 1.Ji JF, Li ZY, Zong XL, Wu XJ, Wu Q, Bu ZD, Wang Y. Oxaliplatin-based regimen as neoadjuvant chemotherapy for Chinese patients with advanced gastric cancer: Preliminary results of a phase II study. 2004 ASCO Annual Meeting Proceedings. Vol 22, No 14S, 2004: 4184 2.Ji JF, Wu AW, Liu YH, Zhang ZT, Wang S, Ye YJ, Li R, Li ZX, Li ZY. Oxaliplatin + 5-fluorouracil/leucovorin (FOLFOX7) as neoadjuvant plus adjuvant treatment versus adjuvant alone in locally advanced resectable gastric cancer: BJSA-01 study design and interim results. 2007 Gastrointestinal Cancers Symposium Abstract No: 39 3.Jia-fu Ji; Xi-yao Zhong; Lian-hai Zhang. OR-10-006 (ORAL PRESENTATION)- Overexpression of mrp14 in gastric carcinoma: correlation with lymph node metastasis and TNM stages. May 10, 2007 International Gastric Cancer Congress (IGCC) Sao Paulo, Brazil 主要的專著、譯著： 1.主編：《癌癥治療新方法》金盾出版社 2004年09月 2.主編：《防御癌患：癌病防治知識(shí)手冊(cè)》華文出版社 2005年05月 3.主編：《腫瘤組織標(biāo)本庫(kù)常用技術(shù)手冊(cè)》科學(xué)出版社2006年7月 4.主編：《胃癌防治新觀念》人民軍醫(yī)出版社 2006年11月 5.主編：《抗癌科普叢書解析胃癌》人民衛(wèi)生出版社2008年11月 6.主編：《普通外科疾病診治思路》科學(xué)出版社 2009年01月 7.主譯：《Bethesda 臨床腫瘤學(xué)手冊(cè)》科技文獻(xiàn)出版社 2005年05月 8.主譯：《牛津臨床腫瘤學(xué)手冊(cè)》人民衛(wèi)生出版社出版時(shí)間：2006年03月
胃癌、結(jié)直腸癌、后腹膜、腹部腫瘤?
